Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...

Single-celled eukaryotes, such as the mold Dictyostelium discoideum and amoebae, use phagocytosis for feeding. In higher eukaryotes, the phagocytes of the immune system, including neutrophils, ...

The following is a summary of “Elevated Fcy receptor expression augments pro-inflammatory macrophage phagocytosis in systemic sclerosis and associated rheumatic diseases,” published in the December ...

This study unveiled the role of Lrrk2 gene in regulating macrophage polarization and immune response. This finding provides ...

The lysosomes fuse with the phagosomes containing the ingested microbes and the microbes are destroyed Phagocytosis. leukocyte and virus. Phagocytosis. leukocyte and virus. Macrophage is a white blood ...

Phagocytosis. Neutrophil that uses its plasma membrane to engulf a bacterium. From endocytosis to exocytosis. educational scheme. Digestion process in phagocyte. immune system mechanism. vector ...

IMC-002 is a fully human IgG monoclonal antibody designed to block CD47–SIRP-α interaction in order to promote the phagocytosis of cancer cells by macrophages. It binds to human CD47 with an ...

Objectives To study macrophage functions in SSc with a focus on Fosl-2 as a potential regulator. Conclusion For the first time, we showed an increased expression of Fosl-2 and boosted phagocytic ...

COPD patients experience chronic inflammation and defective innate immunity, largely driven by macrophage dysfunction. In established disease, COPD macrophages have impaired phagocytosis of bacteria ...

kuleuven.be Intestinal resident macrophages are at the front line of host defence at the mucosal barrier within the gastrointestinal tract and have long been known to play a crucial role in the ...