This emphasizes the need to develop criteria that distinguish transcriptional noise from transcription with a biological function. In the classic view of the transcriptome, RNA polymerase ...

The platform’s scalability, rapid production and relatively straightforward manufacturing process mean that mRNA therapeutics are a powerful alternative to traditional small molecule drugs and DNA ...

InDevR partners with Aldevron to describe how the VaxArray 5′CapQ assay can be used to measure intact mRNA in a single assay to streamline bioprocess development.

Researchers at Tel Aviv University have achieved a breakthrough in drug delivery: they have successfully transported lipid nanoparticles encapsulating messenger RNA (mRNA) to the immune system of ...

Using a novel, RNA-based approach, we sought to restore this ... We used lipid nanoparticles to deliver mRNA and siRNA to human PCa cells to evaluate our technique's ability to both restore ...

Aldevron, a global leader in the production of DNA, RNA and protein, has launched its latest innovation, Alchemy™ cell-free ...

The intracellular barriers include endosomal escape, RNA sensors ... “Larger mRNA-based therapeutics are synthesised by in vitro transcription, which is not amenable to extensive nucleotide ...

CREATE employs a modified L1 mRNA to carry a payload gene, and a Cas9 nickase to facilitate targeted editing by L1-mediated reverse transcription and integration without relying on ... Together, these ...

This was problematic because these molecules are used as starting material for in vitro transcription ... RNA integrity. This is a key critical quality attribute of newly developed mRNA-based ...

After hours: January 31 at 6:07:05 PM EST Loading Chart for RNA ...