Viral vectors expressing proneural genes can stimulate adult mammalian retinal glia to become immature neurons. These glia-derived neurons share properties with the bipolar, amacrine and retinal ...

An abnormal form of the tau protein found to accumulate in the brains of Alzheimer's disease patients also accumulates in the ...

This study demonstrates the critical role of Afadin on the generation and maintenance of complex cellular layers in the mouse retina. The data are solid, which provides important insights into how ...

One area where it is making a difference is in the understanding of retinal ganglion cell (RGC ... properties characteristic of healthy RGCs. Single-cell RNA sequencing played a pivotal role ...

"When we saw unique changes in NZO's retinal ganglion cells at the molecular level, sure enough, we saw drastic functional changes in those cells." These models will allow researchers to study how ...

Abstract: Early retinal vascular changes in diseases such as diabetic retinopathy often occur at a microscopic level. Accurate evaluation of retinal vascular networks at a micro-level could ...

The authors examined whether aberrantly-projecting retinal ganglion cell in albino mice innervate a separate population of thalamocortical neurons, as would be predicted for Hebbian learning rules.