D tumoroid models transform cancer research, accurately reflecting tumor biology and enabling effective drug testing and ...

Developing organoids-on-a-chip technology further enhances their utility by simulating the tumor microenvironment and facilitating interactions between multiple organs and tissues, thus enabling large ...

While these organoids are derived from cancer cell lines and don’t accurately recapitulate the complexity of the tumor microenvironment, the team plans to test their approach using patient-derived ...

Select the journal/section where you want your idea to be submitted: The immune components of the tumor microenvironment (TME) play a significant role in either promoting or inhibiting tumor growth.

Brain Tumor Organoids Accurately Model Patient Response to CAR T Cell Therapy Dec. 9, 2024 — Researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM ...

Tongue cancer (TC) cells can enter a chemo-resistant state by activating pathways related to autophagy and cholesterol synthesis, report researchers. Using a large-scale library of TC organoids ...

Interestingly, these processes are all sensitive to the concentration of oxygen present in the microenvironment. Rapidly proliferating cells cause the NSCLC tumor to extend beyond the oxygen ...