Centrosomes are essential organelles in cells that play a critical role in organizing microtubules, which are structural components that help maintain cell shape and facilitate cell division.
A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8 + T cell division for the generation of memory precursor cells.
For almost a century, our understanding of the tiny structure at the centre of the cell called the centrosome was limited to its ability to organize mitotic spindles and other microtubule arrays.
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cancer cells often display centrosome ...
A recent "Cell Reports" paper by the Oxenius group (IMB) demonstrates a role of targeted centrosome inheritance during CD8+ T cell division for the generation of memory precursor cells. CD8+ T cells ...
This discovery sheds light on how tissue-resident memory CD8 T cells adapt to their location in the body, ensuring a coordinated and effective immune response and how microenvironments and ...