Summary: Microglia, the brain’s immune cells, play vital roles in clearing toxins and maintaining neuronal health but can also contribute to neurodegenerative diseases if overactive. New research ...

Microglia are a type of small macrophage-like glial cell in the central nervous system. Microglia can engage in phagocytosis, and are involved in immune responses within, as well as the ...

Figure 3. Wnt/β-catenin and NF-κB signaling pathways. Wnt/β-catenin signaling pathway: When Wnt ligands bind to the Frizzled receptor on the membrane of astrocytes, they activate DSH (Disheveled) ...

This review includes an overview of post-translational modifications, alterations in microglia-specific biomarkers, and possible mechanistic pathways that may link epigenomic modifications to ...

I am delighted to share our two latest publications, one on Targeted Protein Degradation platform to modulate Wnt signaling (https://lnkd.in/ggWYAz9T), and the other ...

Department of Neurosurgery, The Second Affiliated Hospital of Xi’an Jiao Tong University, Xi’an 710004, P.R. China Department of Orthopaedics, Xijing Hospital, The Fourth Military Medical University, ...

The Ireland Women’s National Team (WNT) will host Türkiye in Tallaght Stadium on Friday, February 21st in their first game of the 2025 UEFA Nations League. The Girls in Green will kick off their ...

Our study reveals two novel functions of transcription factor FOXG1 in controlling both the expression of FGF family ligands in cortical neurons, as well as the sensitivity of progenitors to these FGF ...

Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen DK-2100, Denmark ...