The first reaction in the 3-hydroxypropionate carbon dioxide-fixation cycle is the carboxylation of acetyl-CoA; the carbon dioxide acceptor is then regenerated in a cyclic process, with 3 ...

The mechanism observed in the experiments, known as the reverse water-gas shift reaction, bears a striking resemblance to the acetyl-CoA pathway utilized by certain bacteria and archaea.

We see a similar reaction in the pathway some bacteria and archaea use to turn carbon dioxide into food. This pathway is called the "acetyl-CoA" or "Wood-Ljungdahl" pathway. It is proposed to be ...