The central organelle within the hepatocyte that stores excess fat is the lipid droplet (LD). Scores of different proteins control the formation and use of LDs. A deficit in LD breakdown is believed ...

The researchers subsequently validated CePA's high efficiency and safe mTOR inhibition capacity ... protect HFCFG-induced MASH by regulating lipid droplet accumulation and lipid deposition in ...

This study aimed to determine the role of Reptin in mammalian adult liver. Conclusion We show here that the AAA +ATPase Reptin is a regulator of mTOR signalling in the liver and global glucido-lipidic ...