The answer may lie, in part, in the innate mechanisms of antigen binding by professional APCs. DCs and macrophages express a variety of lectins and scavenger receptors that facilitate direct or ...

This image shows the structure of an antibody (Y-shaped) and how it binds to different types of antigens (color-coded shapes at the top). The antibody's binding sites, located at the ends of its arms, ...

Monoclonal antibodies like etesevimab have lost efficacy against Omicron subvariants, necessitating innovative solutions.

Multi-laser picodroplets can be used in single cell analysis, sorting and dispensing - discover how in this article.

A recent study provides insight into how antigen binding primes T cells to be at the forefront of the immune response. The research team hypothesized that binding of the antigen to the T-cell receptor ...

Proteintech has designed recombinant antibodies featuring the company's FcZero backbone, engineered to silence the Fc domain ...

In a study challenging a long-held doctrine of antibody binding -- which states that a single antibody corresponds to just one antigen, fitting it like a lock fits a key -- researchers have created a ...

The organelle’s acidic environment triggers the release of the antigens, which continue onto lysosomal degradation. The now free IgGs bind to the neonatal Fc receptor (FcRn), which protects them from ...

Immunotherapies use antibodies—proteins that bind to cell markers called antigens—to target and eliminate the antigen. But ...

The irradiated tumor demonstrates higher 7E11 binding (here labeled with Cy5.5) in this maximum-intensity projection ... Targeting the internal epitope of prostate-specific membrane antigen with 89 Zr ...