In a recent study, scientists have introduced an innovative imaging technique that provides an unparalleled view of the bone ...

Bone marrow plays a crucial role in maintaining hematopoietic stem cells and bone homeostasis. However, research has been ...

In a recent study, scientists have introduced an innovative imaging technique that provides an unparalleled view of the bone marrow's intricate ...

The paper, “Breast cancers that disseminate to bone marrow acquire aggressive phenotypes through CX43-related tumor-stroma tunnels,” appears in the Journal of Clinical Investigation.

The researchers investigated how breast cancer cells interact with bone marrow stromal cells. They used co-culture models where breast cancer cells (MCF7 or T47D) were grown directly with ...

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, ...

The paper, "Breast cancers that disseminate to bone marrow acquire aggressive phenotypes through CX43-related tumor-stroma tunnels," appears in the Journal of Clinical Investigation. Estrogen ...

Immune complexes, like the inflammasome, help protect stem cells from cancer by removing surface receptors and suppressing ...

The Food and Drug Administration (FDA) has approved Ryoncil ® (remestemcel-L-rknd) for the treatment of steroid-refractory acute graft vs host disease (SR-aGvHD) in pediatric patients 2 months of age ...

Kimberlin, who previously collaborated with Dr. Jonas Salk to develop the first FDA-approved cell-based immunotherapy, ...

Types of Bone Metastatic Tumors Cytokines secreted by DTCs stimulate osteoclastogenesis. DTCs also co-opt stromal and blood cells of the marrow to induce osteolysis. DTCs can activate osteomimicry ...