The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

Furthermore, gene expression changes were modeled using ... while microglia displayed increases in inflammatory markers like Ildr2 and Ccl4. Glial cells, such as astrocytes and oligodendrocytes ...

Gene expression is the generation of a functional gene product from the information encoded by a gene, through the processes of transcription and translation. Gene products are often proteins ...

Each gene tells a cell to make a specific molecule, but this isn't performed by the DNA itself. Instead, the information is relayed to cellular machinery by a molecule called messenger RNA.

In synovial fluids from patients with OA, levels of CCR2 ligands (CCL2, CCL7 and CCL8) but not CCR5 ligands (CCL3, CCL4 and CCL5) were elevated ... HR cultured and performed the in vitro stimulation ...

Gene regulation refers to the mechanisms that act to induce or repress the expression of a gene. These include structural and chemical changes to the genetic material, binding of proteins to ...

Jan. 21, 2025 — Trypanosomes are parasites that cause sleeping sickness, Chagas disease, and various animal diseases. Diagnosis and treatment remain complex and no effective vaccine has been ...

对DEN-CCl4处理的小鼠肝脏的分析表明 ... 参考资料： 1.Zhang Q, Wei T, Jin W, Yan L, Shi L, Zhu S, et al. Deficiency in SLC25A15, a hypoxia-responsive gene, promotes hepatocellular carcinoma by reprogramming glutamine ...

1 Department of Immunology, Harvard Medical School, Boston, MA, United States 2 The Ragon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT) and Harvard, ...

QRT-PCR assays for PVR (Hs00197846_m1) and PVRL2 (Hs00607609_m1) were performed with TaqMan Gene Expression Assays (Applied Biosystems), with 18s assayed for normalization. For absolute quantification ...

New work by Columbia researchers has turned a textbook principle of genetics on its head and revealed why some people who carry disease-causing genes experience no symptoms. Every biology student ...

Mission Statement: Evidence-based Complementary and Alternative Medicine (eCAM) is an international, peer-reviewed journal that seeks to understand the sources and to encourage rigorous research ...