Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

Cells have surface receptors called integrins that bind to repetitive domains present on the extracellular matrix (ECM) ...

The EXODUS system is an advanced exosome isolation technology, offering significant improvements in yield, purity, and ...

Peptides, as versatile biomolecules, continue to gain traction in various scientific fields due to their wide range of ...

Tweaking the spacing between binding domains on the ECM surrounding cancer cells can boost their killing via ultrasound ...

Brian's research focuses intersections between circadian rhythm and cancer. He utilizes cell line and mouse models of MYC-driven lung cancer to focus on how amplified MYC and metabolic stress disrupt ...

The intricate interplay between actomyosin contractility and extracellular matrix (ECM ... existing paradigms by accurately determining the optimal cell elongation at matrix-driven steady-state ...

This article examines viral and non-viral vectors in gene therapy, highlighting their mechanisms, advantages, and limitations in genetic material delivery.

Researchers identified two anoikis-related genes linked with CTEPH, and that may serve as diagnostic biomarkers or treatment ...

Fas ligand (CD95L) is synthesized both on the cell surface membrane and in a soluble ... We show here that extracellular matrix proteins interact with soluble CD95L and potentiate its pro ...

hku.hk; Dr Helen H N Yan; yanhelen{at}hku.hk Objective Cell-cell (CC) and cell-matrix (CM) adhesions are essential for epithelial cell survival, yet dissociation-induced apoptosis is frequently ...

Newly discovered brain cells count each bite before sending the order to cease eating a meal. Columbia scientists have found specialized neurons in the brains of mice that order the animals to ...