Before arriving at Janelia three years ago, Postdoctoral Scientist Antonio Fiore was designing and building optical instruments like microscopes and spectrometers. Fiore, a physicist by training, came ...

New research has uncovered a complex interplay between extracellular matrix (ECM) structure and the transcriptional responses of cancer cells, showing how they alter their gene expression to ‘escape’ ...

such as when cells interact with the surrounding extracellular matrix or with their immediate neighbors. This type of signaling is especially important to the structure and function of tissues.

A pioneering study has revealed that increased stiffness in the extracellular matrix (ECM) of spinal discs impairs energy ...

New research published in Nature Communications reveals how cancer cells are altered by their surroundings, enabling them to ...

Scientists have developed Rhobo6, a light microscopy probe that reveals extracellular matrix structures in live tissues, advancing biological research and disease diagnostics. Rhobo6 is a light ...

It is now clear that an individual cell can change how it moves in response to the material surrounding it. Petrie's lab is interested in understanding how the structure of the three-dimensional (3D) ...