an orally bioavailable farnesyl transferase inhibitor combination with alpelisib for patients with PIK3CA-dependent HNSCC; and KO-2806, a farnesyl transferase inhibitor for the treatment of solid ...
an orally bioavailable farnesyl transferase inhibitor combination with alpelisib for patients with PIK3CA-dependent HNSCC; and KO-2806, a farnesyl transferase inhibitor for the treatment of solid ...
Farnesyl diphosphate synthase (FPPS) is a key enzyme in this pathway, and its inhibitors have garnered significant attention for their potential therapeutic applications, particularly in cancer ...
Expression and/or activity of HMG-CoA reductase, farnesyl transferase and geranylgeranyl transferase have been associated with cell proliferation, and aberrant expression of these enzymes seems to ...