Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

In this study, we identify an E3 ubiquitin ligase, tripartite motif-containing protein 32 (TRIM32), as a key regulator of hepatic insulin signaling that targets the insulin receptor (INSR) for ...

(NEXSTAR) – In-N-Out Burger is planning to bring its mustard-grilled burgers and spiritual fountain sodas to plenty of new locations in the coming years, with a handful of those restaurants ...

A novel cell-free assay and ribosome profiling provide insights into re-initiation factors and their specificity. A new in vitro re-initiation assay using cell lysates allows investigation of ...

State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210023, China ...

Non-lysine ubiquitination is chemically distinct, and its physiological importance is emerging. Here, we couple chemically and chemoenzymatically synthesized ubiquitinated lysine and threonine model ...