In the past 13 years, more than 100 point mutations and innumerable rearrangements of mitochondrial DNA (mtDNA) have been associated ... affect various protein subunits of complex I and complex ...

Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen ...

Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen species (ROS) management and Ca2+ signaling.

A novel mechanism that enables cells to maintain energy production even when their main power supply drops/fails has been ...

The newly reported research has uncovered one mechanism, which they found is controlled by the mitochondrial ... the MCJ protein could be a new therapeutic target to correct diseases associated ...