This study reveals that PRMT1 overexpression drives tumorigenesis of acute megakaryocytic leukemia (AMKL) and that targeting PRMT1 is a viable approach for treating AMKL. While the evidence, based ...

Pathway 5 (steps 1–2–3 in Figure 4a) is a hybrid pathway, which includes a chemical step converting acetate to acetoacetate. Examining the patent literature suggested this step was likely misannotated ...