Cells synthesize acetyl-CoA using nutrients, such as acetate, derived from food. When a threat is detected, cells add acetyl-CoA to certain proteins, which then unlock access to the genetic ...

Scientists from the Lebanese American University investigated the role of acetyl-CoA synthetase short chain family member 2 (ACSS2) in inflammatory bowel disease, including ulcerative colitis and ...

Sodium acetate is converted to acetyl-CoA once inside cells. In a mouse model, the study confirmed that sodium acetate ...

Through producing acetyl-CoA from acetate, ACSS2 epigenetically controls gene expression. However, whether and how ACSS2 regulates senescence remains unclear. Here, the authors link ACSS2 ...