The first reaction in the 3-hydroxypropionate carbon dioxide-fixation cycle is the carboxylation of acetyl-CoA; the carbon dioxide acceptor is then regenerated in a cyclic process, with 3 ...

SLC25A1 drives citrate export from the mitochondria to the cytosol, where it fuels acetyl-CoA synthesis by ATP citrate lyase (ACLY). This acetyl-CoA supply sustains FSP1 acetylation and prevents its ...

Acetyl-CoA is formed from glucose, fatty acids, ketogenic amino acids. · Acetyl-CoA can be (a) oxidized to CO 2 and H 2 O by TCA cycle and Oxi-Pho and (b) used for synthesis of ketone bodies and fatty ...