SLC25A1 drives citrate export from the mitochondria to the cytosol, where it fuels acetyl-CoA synthesis by ATP citrate lyase (ACLY). This acetyl-CoA supply sustains FSP1 acetylation and prevents its ...

Short-chain fatty acids (SCFAs) like propionate and butyrate are critical byproducts of dietary fiber digestion. These ...

Then again, they are social hornets, and heavy drinking may be part of their party culture. Ha ha. It’s not only humans who ...

A testing service will be available this spring to help farmers and agronomists rapidly investigate suspected cases of ...

In the Fall 2024 grant cycle, American Cancer Society invests more than $12 million in new exploratory and translational grants. Last Fall, the American Cancer Society (ACS) released the full list of ...

Propionyl-CoA and butyryl-CoA levels increased in a dose-dependent manner, correlating with higher histone modifications, while acetyl-CoA levels ... suppression of cell cycle regulators.

In addition, the activity of key rate-limiting enzymes involved in very long-chain fatty acid biosynthesis and β-oxidation—specifically acetyl-CoA carboxylase, fatty acid synthase ... In addition, 10 ...