uhnresearch.ca Objectives Mammalian target of rapamycin (mTOR) (a serine/threonine protein kinase) is a major repressor of autophagy, a cell survival mechanism. The specific in vivo mechanism of mTOR ...

In diatoms, a type of microalgae, ACBPs have been shown to be essential for lipid droplet degradation during stress recovery. A study identified a specific ACBP in the diatom Phaeodactylum ...

Globally, breast cancer represents the most common cancer and the primary cause of death by cancer in women. Lipids are crucial in human physiology, serving as vital energy reserves, structural ...

Intracellular lipid transport can occur by flip‐flop from one side of a bilayer to the other ... lysosomal mTOCRC1 is activated and stimulates mitochondrial oxidative pathways and mtDNA synthesis 247.

In this study, we used temporal metabolomics on HeLa cells to show that MTCH2 deletion results in a high ATP demand, an oxidized cellular environment, and elevated utilization of lipids, amino acids, ...

"Driven by a keen interest in lipid droplet functions in aging and disease, we initiated this fruitful collaboration to harness cutting-edge SRS technology for studying lipid metabolism in ...

No. 1 Teaching Hospital, Norman Bethune College of Medicine, Jilin University, Changchun, Jilin, China Thyroid-associated ophthalmopathy (TAO), an autoimmune disease closely related to thyroid ...

Unsaturated fats are an essential part of your daily diet. Your body uses fats for energy, to keep cells working, produce hormones, and help your body absorb oil-based vitamins (A, D, E, and K). Since ...