Evaluation of human MSCs cell cycle, viability and ... - PubMed
Mesenchymal stem cells (MSCs) have the potential to differentiate into distinct mesenchymal tissue cells. They are easy to expand while maintaining their undifferentiated state, which suggests that these cells could be an attractive cell source for tissue engineering of cartilage.
Multi-omics analysis of human mesenchymal stem cells shows cell …
2023年7月20日 · In this study, we profile the single-cell transcriptomes of MSCs isolated from adipose tissue (AD), bone marrow (BM), placental chorionic membrane (PM), and umbilical cord (UC).
Cell-cycle phases and genetic profile of bone marrow-derived
Human mesenchymal stromal cells (MSCs) expanded in vitro for cell therapy approaches need to be carefully investigated for genetic stability, by employing both molecular and conventional karyotyping. Reliability of cytogenetic analysis may be hampered in some MSC samples by the difficulty of obtaini …
The Life and Fate of Mesenchymal Stem Cells - PMC
Mesenchymal stem cells (MSC) are present throughout the body and are thought to play a role in tissue regeneration and control of inflammation. MSC can be easily expanded in vitro and their potential as a therapeutic option for degenerative and ...
Mesenchymal stem cell perspective: cell biology to clinical progress
2019年12月2日 · MSCs have become widely studied over the past ~30 years for their interesting cell biology, broad-ranging clinical potential, and as a central building block in the rapidly growing field of...
Mesenchymal stem cell perspective: cell biology to clinical progress
MSC cell biology—microheterogeneity, temporal stochasticity and diversity at the single cell level. The defining characteristics of a vertebrate stem cell are the ability to divide (symmetrically or asymmetrically), to be motile, to differentiate to multiple lineages and to become organized into multifunctional groupings.
An overview of mesenchymal stem cells and their potential …
Mesenchymal stem cells (MSCs) are among the most studied stem cells due to their unique characteristics, such as self-renewal and developmental potency to differentiate into numerous cell types. MSC use has fewer ethical challenges compared with other types of stem cells.
Single cell transcriptomic analysis of human mesenchymal …
2019年5月8日 · Mesenchymal stem cells (MSCs) are a population of multipotent cells with a superior ability to promote tissue repair by regulating regeneration and inflammation. Effective application of MSCs...
[Effects of MSC on cell cycle, phenotype and cytokine ... - PubMed
Aim: To study the effect of human bone marrow derived mesenchymal stem cell (MSC) on T cell cycle and activation, and to investigate the inhibitory effect of MSC on T cell proliferation and the underlying mechanism.
Mesenchymal Stem Cell Migration and Tissue Repair - PMC
Bone marrow-derived mesenchymal stem cells (BMSCs) are the most frequently used stem cells in cell therapy and tissue engineering. However, it is prerequisite for BMSCs to mobilize from bone marrow and migrate into injured tissues during …