Tetrathiomolybdate, an orally active anti-copper agent, reduces copper levels in the body. Tetrathiomolybdate has a protective effect on collagen-induced arthritis in mice. …

2007年10月21日 · Tetrathiomolybdate is an oral, small-molecule, anticopper agent that is highly specific for lowering the levels of free copper in serum. COPREXA has completed pivotal …

2021年8月23日 · Tetrathiomolybdate (TM) is a novel, copper-depleting compound associated with promising survival in a phase II study of patients with high-risk and triple-negative breast cancer.

Tetrathiomolybdate (TTM) is a copper chelator that has also demonstrated antiangiogenic, antifibrogenic and anti-inflammatory actions in preclinical studies.

2015年11月13日 · 临床研究发现，癌症患者血浆中铜离子的浓度与肿瘤的恶化程度以及对药物治疗的反应相关。 通过铜离子螯合剂 四硫钼酸盐（Tetrathiomolybdate，TM）减少体内铜离子的 …

Tetrathiomolybdate is an orally bioavailable metal copper (Cu) chelator, with potential antiangiogenic, anti-metastatic and antitumor activities. Upon oral administration, …

View tetrathiomolybdate Datasheet. Tetrathiomolybdate (TM)通过独特的硫桥Mo2S6O2簇诱导细胞铜外排蛋白ATP7B的金属结合域 (WLN4)的二聚化，用于临床治疗威尔逊病 (Wilson’s …

2024年4月1日 · Bis-choline tetrathiomolybdate (TTM) is a potent copper chelator that may be associated with a lower risk of inducing paradoxical neurological worsening than conventional …

2019年1月1日 · Bis-choline tetrathiomolybdate (TTM) is an emerging novel first-in-class copper-protein-binding agent that addresses several concerns encountered with the currently …

2019年1月1日 · Bis-choline tetrathiomolybdate (TTM) is an emerging novel first-in-class copper-protein-binding agent that addresses several concerns encountered with the currently …