Since about 15 mmol of calcium is excreted into the intestine via the bile per day, [1] the total amount of calcium that reaches the duodenum and jejunum each day is about 40 mmol (25 mmol from the diet plus 15 mmol from the bile), of which, on average, 20 mmol is …

2023年8月14日 · Calcium homeostasis is maintained by actions of hormones that regulate calcium transport in the gut, kidneys, and bone. The 3 primary hormones are parathyroid hormone (PTH) 1,25-dihydroxyvitamin D-3 (Vitamin D3), and calcitonin.

2023年5月17日 · In this chapter, we review calcium and phosphate homeostasis including the critical organs involved (skeleton, parathyroids, GI tract, kidneys etc.) as well as the hormones (PTH, vitamin D, FGF23, calcitonin) that regulate calcium and phosphate.

This brief review focuses on calcium balance and homeostasis and their relationship to dietary calcium intake and calcium supplementation in healthy subjects and patients with chronic kidney disease and mineral bone disorders (CKD-MBD).

This brief review focuses on the key mechanisms in the gut, kidney, and bone involved in the regulation of calcium metabolism in humans. It provides an overview of calcium balance and homeostasis in health.

2024年1月8日 · Calcium is physiologically classified as intracellular or extracellular. Intracellular calcium is key in many important physiologic functions, including muscle contraction, hormone secretion, glycogen metabolism, and cell division.

Calcium (Ca +2) is a divalent cation that plays a critical role in numerous body functions such as skeletal mineralization, signal transduction, nerve conduction, muscle contraction, and blood coagulation. Ca +2 metabolism is linked to magnesium (Mg +2) and phosphate metabolism.

2024年4月8日 · There are three molecules which regulate the amount of calcium in the blood and ensure it is maintained within the normal range. These are calcitriol (vitamin D), parathyroid hormone and calcitonin.

The adaptation of calcium metabolism during physiologic challenges relies on flexibility of absorption in the gut, excretion through kidney, and buffering properties of bone.

Calcium metabolism is guaranteed by three main players: PTH (ParaThyroid Hormone), Vitamin D, and FGF23 (Fibroblast Growth Factor 23). They synergistically act in a complex hormonal crosstalk within the parathyroid-intestine-bone-kidney axis.