- Collagen is a protein that forms a flexible framework in the bone’s matrix, contributing to its strength and resilience.了解详细信息：Collagen is a protein that forms a flexible framework in the bone’s matrix, contributing to its strength and resilience.et-chem.com/why-are-collagen-fibers-a-critical-com…
This review focuses on the acquisition and processing of collagen, the mechanisms involved in collagen-induced osteogenesis, the biomimetic materials composed of collagen and different materials, and the application of collagen-based bioactive materials in bone tissue engineering.
www.sciencedirect.com/science/article/pii/S026412…This review describes the interactions of type I collagen with the mineral and the contribution of the orientations of the collagen fibers when the bone is submitted to mechanical forces.
pubmed.ncbi.nlm.nih.gov/16341622/Collagen mutations can affect the production, assembly, or stability of collagen fibers in bone. For example, mutations in the COL1A1 or COL1A2 genes, which encode type I collagen, can lead to osteogenesis imperfecta (OI), a group of genetic disorders characterized by brittle bones that are prone to fracture.
www.sciencedirect.com/science/article/pii/S030146…Collagen fibres Collagen is a protein in the form of fibre and is the body's ‘glue’. It possesses two major properties, great tensile strength and relative inextensibility, and forms the major fibrous component of connective tissue structures, i.e. tendons, ligaments, fascia, sheaths, bursae, bone and cartilage.
www.sciencedirect.com/topics/medicine-and-dentis… Collagen-based biomaterials for bone tissue engineering
- 已发布: 2021/11/15
- DOI: 10.1016/j.matdes.2021.110049
- 引用者: 0
- Keywords: Bone tissue engineering; Biomaterials; Collage…
In recent years, there has been increasing interest in using biomimetic materials for bone tissue engineering. However, the high immunogenicity and low mechanical properties of biomimetic materials limit their applications in vivo. As an essential component of the extracellular matrix in bone tissue...The role of collagen in bone strength - PubMed
This review describes the interactions of type I collagen with the mineral and the contribution of the orientations of the collagen fibers when the bone is submitted to mechanical forces.
Type 1 collagen: Synthesis, structure and key functions in bone ...
2024年3月1日 · Collagen mutations can affect the production, assembly, or stability of collagen fibers in bone. For example, mutations in the COL1A1 or COL1A2 genes, which encode type I …
Collagen Fiber - an overview | ScienceDirect Topics
Collagen fibres Collagen is a protein in the form of fibre and is the body's ‘glue’. It possesses two major properties, great tensile strength and relative inextensibility, and forms the major fibrous …
Molecular mechanics of mineralized collagen fibrils in …
2013年4月16日 · We apply an in silico mineralization scheme based on a Monte Carlo approach, and identify molecular structures of nascent bone for different mineral densities, from 0% (pure collagen...
Why Are Collagen Fibers a Critical Component of Bone?
2024年3月20日 · Collagen is a protein that forms a flexible framework in the bone’s matrix, contributing to its strength and resilience. This article delves into why collagen fibers are an indispensable component of bone and how they …
Biomechanical Characteristics and Analysis Approaches of Bone …
From the most basic amino acids and HA crystals to mineralized collagen fibers and even to the whole bone, each layer is extremely complex, which also gives us a great challenge to …
Bundling of collagen fibrils influences osteocyte network …
2023年12月12日 · The bone increases its thickness as a matrix through repeated collagen fiber formation. Hydroxyapatite is deposited into collagen fibers, where they form calcified nodules.
Collagen Type I Biomaterials as Scaffolds for Bone …
2021年2月17日 · When combined with bone marrow-derived mesenchymal stem cells (BM-MSCs), collagen tubes supported better regeneration of peripheral nerve fibers across a 3-mm nerve gap, thus demonstrating that these tubes …
Collagen Fiber Orientation Is Coupled with Specific …
2021年1月6日 · As the adaptive capabilities of bone are portrayed in its nano- and microstructure, the existence of dark and bright osteons with contrasting preferential collagen fiber orientation (longitudinal and oblique-angled, …
