Desmosome is a intercellular junction in animal cell. A desmosome (/ ˈdɛzməˌsoʊm /; [1][2] "binding body"), also known as a macula adherens (plural: maculae adherentes) (Latin for adhering spot), is a cell structure specialized for cell-to- cell adhesion.

2017年4月28日 · Desmosomes Definition. Desmosomes are a type of anchoring junction in animal tissues that connect adjacent cells. Anchoring junctions are button-like spots found all around cells that bind adjacent cells together.

Desmosomes are adhesive intercellular junctions that mechanically integrate adjacent cells by coupling adhesive interactions mediated by desmosomal cadherins to the intermediate filament cytoskeletal network.

Desmosomes are one of four intercellular junctions present on the lateral side of neighboring polarized epithelial cells. Tight junctions and adherens junctions (AJs) are restricted to the apical domain, where they form the epithelial barrier and organize cortical actin, respectively.

2008年3月1日 · Desmosomes are intercellular junctions that provide strong adhesion between cells. Because they also link intracellularly to the intermediate filament cytoskeleton they form the adhesive bonds in a network that gives mechanical strength to tissues.

2022年8月19日 · What are desmosomes. What do they do in a cell. Where are they found. What are they made of. Learn their structure with a diagram.

Desmosomes are intercellular junctions that tether intermediate filaments to the plasma membrane. Desmogleins and desmocollins, members of the cadherin superfamily, mediate adhesion at desmosomes.

2011年7月26日 · Desmosomes are specialized adhesive protein complexes that localize to intercellular junctions and are responsible for maintaining the mechanical integrity of tissues. The term ‘desmosome’ was coined by Josef Schaffer in 1920 and has its origins in the Greek words for bond (desmo) and body (soma).

2022年12月30日 · Desmosomes connect the intermediate laments of adjacent cells across adhesion molecules strengthened by a protein plaque. Desmoglein and desmocollin, the adhesion molecules are members of the cadherin family, and the reinforcing plaque contains plakoglobin, which connects the adhesion molecules to the IF linker, desmoplakin.

2024年3月4日 · Desmosomes are specialized structures found in cells that play a vital role in maintaining tissue integrity and strength. These cell junctions are responsible for linking adjacent cells together, forming strong connections that help withstand mechanical stress and promote cellular adhesion.