Immunological synapse - Wikipedia
In immunology, an immunological synapse (or immune synapse) is the interface between an antigen-presenting cell or target cell and a lymphocyte such as a T cell, B cell, or natural killer cell. The interface was originally named after the neuronal synapse, with which it shares the main structural pattern. [1] .
The immunological synapse - PMC
The immunological synapse or kinapse integrates three broad categories of receptors: antigen (TCR), adhesion, and costimulatory/checkpoint. The organization of these receptors in the interface impacts how they function in a way that cannot be predicted without this spatial and temporal information.
T-cell-antigen recognition and the immunological synapse - Nature
2003年12月1日 · We define the 'immunological synapse' as any stable, flattened interface between a lymphocyte or natural killer cell and a cell that they are in the process of recognizing.
The Immune Synapse: Past, Present, and Future - PubMed
Immunological synapses are specialized cell-cell junctions characterized by (1) close apposition of the immune cell membrane with the membrane of another cell driven by adaptive or innate immune recognition, (2) adhesion, (3) stability, and (4) directed secretion.
What is an immunological synapse? - LUMICKS
What is an immune synapse and why is it relevant for cell therapy? An immunological synapse is an interface between an antigen-presenting cell or a target cell and a lymphocyte or a natural killer cell, which is formed in a highly stable, organized manner.
Immune synapses in T-cell activation - ScienceDirect
2006年6月1日 · The contact site between T cells and antigen-presenting cells or T cells and their targets — the immunological synapse — is a highly specialized structure potentially involved in T-cell activation and function.
The immunological synapse - PMC
Initiation of an antigen-specific immune response is based on the interaction between T-cell receptors (TCRs) and major histocompatibility complex proteins that have bound antigenic peptides (MHCps) [3, 4].